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Remove model score from Nallo SNV score config - #145

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remove-model-score
Open

Remove model score from Nallo SNV score config#145
fellen31 wants to merge 1 commit into
masterfrom
remove-model-score

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@fellen31

@fellen31 fellen31 commented May 27, 2026

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Description

Adresses #121.

Number of SNVs uploaded with charmedswan:

  • with model score: 3114
  • without model score: 3114.

By removing ModelScore we are giving:

  • 74 variants +2 RankScore (median 9, top 3 highest: 21, 16, 15)
  • 8 variants +5 RankScore (median 9, top 3 highest: 14, 11, 10)

of the 3042 variants with RankScore > 8.

ModelScore is not used in MIVMIR either. Best guess I think it should be pretty safely be able to remove this section of the rank model without significantly altering the rate of true and false positives.

Changed

  • Removed inheritance model score from Nallo SNV score config

@fellen31 fellen31 linked an issue May 27, 2026 that may be closed by this pull request
@fellen31
fellen31 marked this pull request as ready for review May 29, 2026 11:02
@fellen31
fellen31 requested review from dnil and jemten May 29, 2026 11:02
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How useful is ModelScore?

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