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feat: mcp - #178

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Work done for PGx agent

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📥 Commits

Reviewing files that changed from the base of the PR and between 5bf2268 and 28c5870.

📒 Files selected for processing (131)
  • .github/workflows/check-bioc.yml
  • .gitignore
  • DESCRIPTION
  • Dockerfile
  • NAMESPACE
  • NEWS.md
  • R/GR.R
  • R/GWC.R
  • R/PharmacoSet-accessors.R
  • R/PharmacoSet-class.R
  • R/PharmacoSet-utils.R
  • R/adaptiveMatthewCor.R
  • R/callingWaterfall.R
  • R/class-SignatureClass.R
  • R/computeABC.R
  • R/computeAUC.R
  • R/computeAUC_old.R
  • R/computeAmax.R
  • R/computeDSS.R
  • R/computeDrugSensitivity.R
  • R/computeGR.R
  • R/computeIC50.R
  • R/computeICn.R
  • R/computeSlope.R
  • R/computeSynergy.R
  • R/connectivityScore.R
  • R/cosinePerm.R
  • R/curveFittingPGX.R
  • R/datasets.R
  • R/downloadPSet.R
  • R/downloadSignatures.R
  • R/drugDoseResponseCurve.R
  • R/drugPerturbationSig.R
  • R/filterNoisyCurves.R
  • R/geneDrugPerturbation.R
  • R/geneDrugSensitivity.R
  • R/geneDrugSensitivityPBCorr.R
  • R/geneDrugSensitivityPCorr.R
  • R/getRawSensitivityMatrix.R
  • R/globals.R
  • R/intersectPSets.R
  • R/logLogisticRegression.R
  • R/matthewCor.R
  • R/mergePSets.R
  • R/methods-[.R
  • R/methods-drugSensitivitySig.R
  • R/methods-intersect.R
  • R/methods-subsetTo.R
  • R/methods-summarizeMolecularProfiles.R
  • R/methods-summarizeSensitivityProfiles.R
  • R/plotPSig.R
  • R/rankGeneDrugPerturbation.R
  • R/rankGeneDrugSensitivity.R
  • R/sanityCheck.R
  • R/updateObject-methods.R
  • R/zzz.R
  • README.md
  • codecover.R
  • inst/mcp/PharmacoGx-tools.R
  • inst/mcp/README.md
  • inst/mcp/biomni-mcp-config.yaml
  • inst/mcp/manuscript-architecture.md
  • inst/mcp/run-pharmacogx-mcp.R
  • inst/mcp/tooluniverse-mcp-tools-config.json
  • inst/skills/pharmacogx-agentic-analysis/SKILL.md
  • man/CCLEsmall.Rd
  • man/CMAPsmall.Rd
  • man/GDSCsmall.Rd
  • man/PharmacoSet-accessors.Rd
  • man/PharmacoSet-class.Rd
  • man/PharmacoSet2.Rd
  • man/computeAUC.Rd
  • man/computeAmax.Rd
  • man/computeHSA.Rd
  • man/computeICn.Rd
  • man/computeLoewe.Rd
  • man/computeSlope.Rd
  • man/computeZIPdelta-TreatmentResponseExperiment-method.Rd
  • man/cosinePerm.Rd
  • man/curveFittingPGX.Rd
  • man/dot-computeZIPdelta.Rd
  • man/dot-normalizeBiphasicPars.Rd
  • man/dot-normalizeHillPars.Rd
  • man/dot-pgx_biphasic_curve.Rd
  • man/dot-pgx_hill_curve.Rd
  • man/dot-summarizeSensProfiles.Rd
  • man/downloadPSet.Rd
  • man/downloadPertSig.Rd
  • man/drugDoseResponseCurve.Rd
  • man/drugSensitivitySig-PharmacoSet-method.Rd
  • man/effectToDose.Rd
  • man/filterNoisyCurves.Rd
  • man/fitTwowayZIP.Rd
  • man/hillCurve.Rd
  • man/intersectPSet.Rd
  • man/loeweCI.Rd
  • man/logLogisticRegression.Rd
  • man/mcc.Rd
  • man/plot.PharmacoSig.Rd
  • man/summarizeMolecularProfiles-PharmacoSet-method.Rd
  • man/summarizeSensitivityProfiles-PharmacoSet-method.Rd
  • tests/testthat/test_Hill.R
  • tests/testthat/test_PharmacoSetClass.R
  • tests/testthat/test_PharmacoSet_utils.R
  • tests/testthat/test_bracket_pharmacoset.R
  • tests/testthat/test_computeABC.R
  • tests/testthat/test_computeAUC.R
  • tests/testthat/test_computeAmax.R
  • tests/testthat/test_computeDSS.R
  • tests/testthat/test_computeHSA.R
  • tests/testthat/test_computeIC50.R
  • tests/testthat/test_computeSlope.R
  • tests/testthat/test_computeZIPdelta.R
  • tests/testthat/test_downloadPSet.R
  • tests/testthat/test_drugDoseResponseCurve.R
  • tests/testthat/test_drugPerturbationSig.R
  • tests/testthat/test_drugSensitivitySig.R
  • tests/testthat/test_intersectPSet.R
  • tests/testthat/test_logLogisticRegression.R
  • tests/testthat/test_sanitizeInput.R
  • tests/testthat/test_subsetTo.R
  • tests/testthat/test_summarizeMolecularProfiles.R
  • tests/testthat/test_summarizeMolecularProfiles_missing_ucell.R
  • tests/testthat/test_summarizeSensitivityProfiles.R
  • tests/testthat/test_summarizeSensitivityProfiles_longtable.R
  • tests/testthat/test_unionList.R
  • vignettes/CreatingPharmacoSet.Rmd
  • vignettes/DetectingDrugSynergyAndAntagonism.R
  • vignettes/DetectingDrugSynergyAndAntagonism.Rmd
  • vignettes/PharmacoGx.Rmd
  • vignettes/pharmacogx.bib

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