diff --git a/requirements.txt b/requirements.txt
index 1fcaa35..2b7feae 100644
--- a/requirements.txt
+++ b/requirements.txt
@@ -1,8 +1,8 @@
-flask==2.0.3
+flask==2.2.5
 simplejson==3.17.2
 python-dotenv==0.15.0
-requests==2.25.1
-gunicorn==20.0.4
-gevent==21.1.2
+requests==2.32.2
+gunicorn==22.0.0
+gevent==23.9.0
 biopython==1.78
 werkzeug==2.0.3