diff --git a/services-custom/dynamodb-enhanced/src/main/java/software/amazon/awssdk/enhanced/dynamodb/DynamoDbEnhancedClientExtension.java b/services-custom/dynamodb-enhanced/src/main/java/software/amazon/awssdk/enhanced/dynamodb/DynamoDbEnhancedClientExtension.java
index b66f493bdac8..82cd554a51a7 100644
--- a/services-custom/dynamodb-enhanced/src/main/java/software/amazon/awssdk/enhanced/dynamodb/DynamoDbEnhancedClientExtension.java
+++ b/services-custom/dynamodb-enhanced/src/main/java/software/amazon/awssdk/enhanced/dynamodb/DynamoDbEnhancedClientExtension.java
@@ -32,6 +32,21 @@
 @SdkPublicApi
 @ThreadSafe
 public interface DynamoDbEnhancedClientExtension {
+
+    /**
+     * Determines whether this extension should process operations for the given table.
+     * <p>
+     * This method is called before invoking {@link #beforeWrite} or {@link #afterRead} to allow
+     * extensions to skip processing when they are not configured for a particular table schema.
+     *
+     * @param metadata the table metadata to check
+     * @return {@code true} if this extension should process operations for the table,
+     * {@code false} to skip this extension for the table
+     */
+    default boolean shouldProcess(TableMetadata metadata) {
+        return true;
+    }
+
     /**
      * This hook is called just before an operation is going to write data to the database. The extension that
      * implements this method can choose to transform the item itself, or add a condition to the write operation
diff --git a/services-custom/dynamodb-enhanced/src/main/java/software/amazon/awssdk/enhanced/dynamodb/extensions/AtomicCounterExtension.java b/services-custom/dynamodb-enhanced/src/main/java/software/amazon/awssdk/enhanced/dynamodb/extensions/AtomicCounterExtension.java
index 69a7807bb970..f59d44e2e64d 100644
--- a/services-custom/dynamodb-enhanced/src/main/java/software/amazon/awssdk/enhanced/dynamodb/extensions/AtomicCounterExtension.java
+++ b/services-custom/dynamodb-enhanced/src/main/java/software/amazon/awssdk/enhanced/dynamodb/extensions/AtomicCounterExtension.java
@@ -17,6 +17,7 @@
 
 import static software.amazon.awssdk.enhanced.dynamodb.internal.EnhancedClientUtils.keyRef;
 import static software.amazon.awssdk.enhanced.dynamodb.internal.EnhancedClientUtils.valueRef;
+import static software.amazon.awssdk.enhanced.dynamodb.internal.extensions.AtomicCounterTag.CUSTOM_METADATA_KEY_PREFIX;
 import static software.amazon.awssdk.enhanced.dynamodb.internal.update.UpdateExpressionUtils.ifNotExists;
 
 import java.util.ArrayList;
@@ -29,6 +30,7 @@
 import software.amazon.awssdk.enhanced.dynamodb.DynamoDbEnhancedClient;
 import software.amazon.awssdk.enhanced.dynamodb.DynamoDbEnhancedClientExtension;
 import software.amazon.awssdk.enhanced.dynamodb.DynamoDbExtensionContext;
+import software.amazon.awssdk.enhanced.dynamodb.TableMetadata;
 import software.amazon.awssdk.enhanced.dynamodb.extensions.annotations.DynamoDbAtomicCounter;
 import software.amazon.awssdk.enhanced.dynamodb.internal.extensions.AtomicCounterTag;
 import software.amazon.awssdk.enhanced.dynamodb.internal.mapper.AtomicCounter;
@@ -106,6 +108,11 @@ public static AtomicCounterExtension.Builder builder() {
         return new AtomicCounterExtension.Builder();
     }
 
+    @Override
+    public boolean shouldProcess(TableMetadata metadata) {
+        return metadata.customMetadataObject(CUSTOM_METADATA_KEY_PREFIX, Map.class).isPresent();
+    }
+
     /**
      * @param context The {@link DynamoDbExtensionContext.BeforeWrite} context containing the state of the execution.
      * @return WriteModification contains an update expression representing the counters.
diff --git a/services-custom/dynamodb-enhanced/src/main/java/software/amazon/awssdk/enhanced/dynamodb/extensions/VersionedRecordExtension.java b/services-custom/dynamodb-enhanced/src/main/java/software/amazon/awssdk/enhanced/dynamodb/extensions/VersionedRecordExtension.java
index 907ef521b1ec..459c8fadd758 100644
--- a/services-custom/dynamodb-enhanced/src/main/java/software/amazon/awssdk/enhanced/dynamodb/extensions/VersionedRecordExtension.java
+++ b/services-custom/dynamodb-enhanced/src/main/java/software/amazon/awssdk/enhanced/dynamodb/extensions/VersionedRecordExtension.java
@@ -32,6 +32,7 @@
 import software.amazon.awssdk.enhanced.dynamodb.DynamoDbEnhancedClientExtension;
 import software.amazon.awssdk.enhanced.dynamodb.DynamoDbExtensionContext;
 import software.amazon.awssdk.enhanced.dynamodb.Expression;
+import software.amazon.awssdk.enhanced.dynamodb.TableMetadata;
 import software.amazon.awssdk.enhanced.dynamodb.mapper.StaticAttributeTag;
 import software.amazon.awssdk.enhanced.dynamodb.mapper.StaticTableMetadata;
 import software.amazon.awssdk.services.dynamodb.model.AttributeValue;
@@ -141,6 +142,11 @@ public Consumer<StaticTableMetadata.Builder> modifyMetadata(String attributeName
         }
     }
 
+    @Override
+    public boolean shouldProcess(TableMetadata metadata) {
+        return metadata.customMetadataObject(CUSTOM_METADATA_KEY, String.class).isPresent();
+    }
+
     @Override
     public WriteModification beforeWrite(DynamoDbExtensionContext.BeforeWrite context) {
         Optional<String> versionAttributeKey = context.tableMetadata()
diff --git a/services-custom/dynamodb-enhanced/src/main/java/software/amazon/awssdk/enhanced/dynamodb/internal/extensions/ChainExtension.java b/services-custom/dynamodb-enhanced/src/main/java/software/amazon/awssdk/enhanced/dynamodb/internal/extensions/ChainExtension.java
index ed4166d49a15..a9ccbf6f586c 100644
--- a/services-custom/dynamodb-enhanced/src/main/java/software/amazon/awssdk/enhanced/dynamodb/internal/extensions/ChainExtension.java
+++ b/services-custom/dynamodb-enhanced/src/main/java/software/amazon/awssdk/enhanced/dynamodb/internal/extensions/ChainExtension.java
@@ -99,6 +99,9 @@ public WriteModification beforeWrite(DynamoDbExtensionContext.BeforeWrite contex
         UpdateExpression updateExpression = null;
 
         for (DynamoDbEnhancedClientExtension extension : this.extensionChain) {
+            if (!extension.shouldProcess(context.tableMetadata())) {
+                continue;
+            }
             Map<String, AttributeValue> itemToTransform = transformedItem == null ? context.items() : transformedItem;
 
             DynamoDbExtensionContext.BeforeWrite beforeWrite =