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Update Trex #25

Description

@ncborcherding

Trex overhaul to be compatible with Seurat v5 and move away from reticulate. Similar to Ibex overhaul for the submission to Bioconductor.

Proposed Changes

  • Integration of Ibex with immApex
  • Move towards zenodo hosting of models
  • Updated Seurat object to v5
  • Dedicated basilisk environment
  • Update support for SCE format for runTrex()
  • Update CoNGAfy() to function with all versions of Seurat
  • Update quietTCRgenes() to use VariableFeatures() call for SeuratV5 and backward compatibility.
  • Update annotateDB() (per issue
    • Automate Library Pull
    • Add better support for HLA information/Add to meta data [see issue]
    • Expand matching system beyond edit distance

After these changes the plan will be to submit to bioconductor similar to the recently accepted Ibex.

Activity

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